Racecadotril vs Loperamide
Racecadotril vs. Loperamide for Adult Infectious Diarrhoea: A Comparative Analysis Infectious Diseases General Medicine Internal Medicine About Diarrhoea, defined as three or more loose stools per day, remains a global health concern, especially in its infectious form, which contributes significantly to mortality. Causes may be infectious (bacteria, viruses) or non-infectious. Treatment includes antibiotics, probiotics, and antimotility agents like Loperamide and Racecadotril. While Loperamide is widely used, it may cause adverse effects, such as constipation and is contraindicated in dysentery or bacterial enterocolitis. Racecadotril, a newer anti-secretory agent, reduces fluid loss without affecting motility. Studies and meta-analyses show Racecadotril offers comparable efficacy to Loperamide but with fewer side effects and broader safety, making it a preferable alternative. Racecadotril vs. Loperamide for adult infectious diarrhoea: A comparative analysis Diarrhoea is a preval...